HPV (Human papillomavirus)

HPV (Human papillomavirus)

HPV (Human papillomavirus)

HPV (Human papillomavirus) is the most HPV is the utmost common viral infection of the reproductive tract and anus in both men and women. It also is the cause of precancerous lesions that may progress to cancer. Even though the majority of HPV infections do not cause symptoms and resolve naturally within 1 -2 years, persistent infection with HPV may bring about premalignant glandular or squamous intra-epithelial lesions and cancers especially cervical cancer.

HPV causes

In women In men
Cervical cancer Penile cancer
Vaginal cancer
Valvar cancer
Mouth and throat cancer
Anal Cancer
Genital warts

Types of HPV

Over 100 different types of HPV have been identified. The HPV types are classified as low-risk or high-risk based on their potential for causing cancer. HPV types 6 and 11 have very low oncogenic potential and are rarely associated with cancer. These types of HPV cause almost 100% of anogenital warts. Persistent infections with high-risk, oncogenic HPV subtypes have been widely implicated in the development of cervical cancer due to resulting high-grade cervical cell abnormalities. HPV subtypes 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 68, 69, 73, and 82 are considered high risk. These subtypes are also responsible for many vulvar, vaginal, penile, anal, and oropharyngeal cancers.

HPV prevalence

Around 27,000 cases of HPV related cancers are reported each year in the United States. Over 500,000 globally and 10,000 new cases of cervical cancer in Thailand are diagnosed every year. In fact, cervical cancer is the second most common cause of cancer related death among 20 – 39 years old women globally and the first in Thai women. In each day, 12 Thai women are dead from cervical cancer.


How to get infected

HPV is transmitted through direct skin-to-skin contact with an HPV infected individual. Transmission is correlated with sexual intercourse, both vaginal and anal. Less commonly, HPV can occur through vertical transmission from mother to infant during the intrapartum period.


HPV related disease prophylaxis methods

HPV vaccination, Visual Inspection with acetic acid (VIA), and Pepanicolauo (Pap) smear.